Characteristics and Efficacy of Two Topical Therapeutic Agents for Onychomycosis

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Onychomycosis: rationalization of topical treatment.

BACKGROUND Fungal infection of the nail affects millions of people worldwide and has an estimated prevalence of more than 10% of the general population. OBJECTIVES To determinate the prevalence of fungal infection in toenails, in order to decide the treatment policy for onychomycosis. METHODS We evaluated 331 patients with suspected clinical toenail onychomycosis affecting at least two toen...

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BACKGROUND Distal and lateral onychomycoses are the most frequent forms of onychomycosis, causing subungual hyperkeratosis that usually limits local penetration of antimycotic drugs. Tazarotene exerts anti-inflammatory and immune-modulating activities toward both infective agents and damaged keratinocytes. Given the well-documented efficacy of tazarotene on hyperkeratotic nail psoriasis, we inv...

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Molecular evaluation of candida species as etiologic agents of onychomycosis

Background and Aim: The aim of the present study is rapid and precise identification of yeast species isolated from nail of patients with clinical features of onychomycosis using PCR-RFLP technique. Methods: 50 patients with involvement of 29 fingernails and 21 toenails were enrolled in the study. Different yeast species were identified by conventional mycological. The PCR-RFLP was tested on...

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ژورنال

عنوان ژورنال: Medical Mycology Journal

سال: 2019

ISSN: 2185-6486,2186-165X

DOI: 10.3314/mmj.19.006